Expression and characterization of functional domains of FK506-binding protein 35 from Plasmodium knowlesi

• Main Authors: Goh, Carlmond Kah Wun, Silvester, Jovi, Wan Mahadi, Wan Nur Shuhaida, Chin, Lee Ping, Ying, Lau Tiek, Leow, Thean Chor, Kurahashi, Ryo, Takano, Kazufumi, Budiman, Cahyo
• Format: Article
• Published: Oxford University Press 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/79826/; https://academic.oup.com/peds/article/31/12/489/5497668?login=true
• Institution: Universiti Putra Malaysia

The FK506-binding protein of Plasmodium knowlesi (Pk-FKBP35) is considerably a viable antimalarial drug target, which belongs to the peptidyl-prolyl cis-trans isomerase (PPIase) protein family member. Structurally, this protein consists of an N-terminal FK506-binding domain (FKBD) and a C-terminal t...