In vitro characterization and in vivo performance of mefenamic acid-sodium diethyldithiocarbamate based liposomes

• Main Authors: Jarrar, Qais Bashir Mahmoud, Abdullah, Muhammad Nazrul Hakim, Cheema, Manraj Singh, Zakaria, Zainul Amiruddin
• Format: Article
• Language: English
• Published: Universidade de Sao Paulo 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/80220/1/In%20vitro%20characterization%20and%20in%20vivo%20performance%20of%20mefenamic%20acid-sodium%20diethyldithiocarbamate%20based%20liposomes.pdf; http://psasir.upm.edu.my/id/eprint/80220/; https://www.researchgate.net/publication/336887556_In_vitro_characterization_and_in_vivo_performance_of_mefenamic_acid-sodium_diethyldithiocarbamate_based_liposomes
• Institution: Universiti Putra Malaysia

Mefenamic acid (MFA) is a hydrophobic drug with low dissolution rate. This study aimed to develop stable and reproducible aqueous formulations of MFA using liposomes as drug carriers. The drug entrapment, particles size and drug release profiles, and stability and reproducibility of the liposomes we...