Protective effect of Centella asiatica against D-galactose and aluminium chloride induced rats: behavioral and ultrastructural approaches

• Main Authors: Chiroma, Samaila Musa, Baharuldin, Mohamad Taufik Hidayat, Mat Taib, Che Norma, Amom, Zulkhairi, Jagadeesan, Saravanan, Adenan, Mohd ilham, Mohd Moklas, Mohamad Aris
• Format: Article
• Language: English
• Published: Elsevier 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/81873/1/Protective%20effect%20of%20Centella%20asiatica%20.pdf; http://psasir.upm.edu.my/id/eprint/81873/; https://www.sciencedirect.com/science/article/pii/S075333221833717X?via%3Dihub
• Institution: Universiti Putra Malaysia

Background: Alzheimer’s disease (AD) is a neurodegenerative disorder and the commonest cause of dementia among the aged people. D-galactose (D-gal) is a senescence agent, while aluminium is a known neurotoxin linked to pathogenesis of AD. The combined administration of rats with d-gal and aluminium...