Preparation and evaluation pumpkin seed oil-based vitamin e cream formulations for topical application

Plant seed oil is often incorporated into the cream emulsions to provide multifunctional effects on the skin. In the current study, pumpkin seed oil (PSO) was used to develop a stable oil-in-water emulsion. The study aimed to optimise PSO cream formulation and determine the synergistic effect of the...

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Main Authors: Ong, Teik Siun, Chu, Chee Chin, Tan, Chin Ping, Nyam, Kar Lin
Format: Article
Language:English
Published: Japan Oil Chemists’ Society 2020
Online Access:http://psasir.upm.edu.my/id/eprint/86667/1/Preparation%20and%20evaluation%20pumpkin%20seed%20.pdf
http://psasir.upm.edu.my/id/eprint/86667/
https://www.jstage.jst.go.jp/article/jos/69/4/69_ess19250/_article
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Institution: Universiti Putra Malaysia
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spelling my.upm.eprints.866672022-01-24T11:28:08Z http://psasir.upm.edu.my/id/eprint/86667/ Preparation and evaluation pumpkin seed oil-based vitamin e cream formulations for topical application Ong, Teik Siun Chu, Chee Chin Tan, Chin Ping Nyam, Kar Lin Plant seed oil is often incorporated into the cream emulsions to provide multifunctional effects on the skin. In the current study, pumpkin seed oil (PSO) was used to develop a stable oil-in-water emulsion. The study aimed to optimise PSO cream formulation and determine the synergistic effect of the PSO with vitamin E oil added. The physical properties, antioxidant activities and storage stability of the formulations were analysed. Besides, the synergistic effect of the best formulation was analysed based on α-tocopherol content using ultra-high performance liquid chromatography (UHPLC). The storage stability test was assessed upon storing at 25 ± 2°C and 40 ± 2°C for 12 weeks. The best formulation (20% PSO, vitamin E oil and beeswax) selected showed physically and microbiologically stable. The incorporation of vitamin E oil into the formulation produced with PSO was found to be compatible, as it showed a synergistic effect in the amount of α-tocopherol content (combination index (CI) = 0.98). Thus, PSO had shown its potency to be incorporated into the topical products with a promising potential in delivering additional properties that can nourish the skin. Japan Oil Chemists’ Society 2020-04-03 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/86667/1/Preparation%20and%20evaluation%20pumpkin%20seed%20.pdf Ong, Teik Siun and Chu, Chee Chin and Tan, Chin Ping and Nyam, Kar Lin (2020) Preparation and evaluation pumpkin seed oil-based vitamin e cream formulations for topical application. Journal of Oleo Science, 69 (4). 297 - 306. ISSN 1345-8957; ESSN: 1347-3352 https://www.jstage.jst.go.jp/article/jos/69/4/69_ess19250/_article 10.5650/jos.ess19250
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Plant seed oil is often incorporated into the cream emulsions to provide multifunctional effects on the skin. In the current study, pumpkin seed oil (PSO) was used to develop a stable oil-in-water emulsion. The study aimed to optimise PSO cream formulation and determine the synergistic effect of the PSO with vitamin E oil added. The physical properties, antioxidant activities and storage stability of the formulations were analysed. Besides, the synergistic effect of the best formulation was analysed based on α-tocopherol content using ultra-high performance liquid chromatography (UHPLC). The storage stability test was assessed upon storing at 25 ± 2°C and 40 ± 2°C for 12 weeks. The best formulation (20% PSO, vitamin E oil and beeswax) selected showed physically and microbiologically stable. The incorporation of vitamin E oil into the formulation produced with PSO was found to be compatible, as it showed a synergistic effect in the amount of α-tocopherol content (combination index (CI) = 0.98). Thus, PSO had shown its potency to be incorporated into the topical products with a promising potential in delivering additional properties that can nourish the skin.
format Article
author Ong, Teik Siun
Chu, Chee Chin
Tan, Chin Ping
Nyam, Kar Lin
spellingShingle Ong, Teik Siun
Chu, Chee Chin
Tan, Chin Ping
Nyam, Kar Lin
Preparation and evaluation pumpkin seed oil-based vitamin e cream formulations for topical application
author_facet Ong, Teik Siun
Chu, Chee Chin
Tan, Chin Ping
Nyam, Kar Lin
author_sort Ong, Teik Siun
title Preparation and evaluation pumpkin seed oil-based vitamin e cream formulations for topical application
title_short Preparation and evaluation pumpkin seed oil-based vitamin e cream formulations for topical application
title_full Preparation and evaluation pumpkin seed oil-based vitamin e cream formulations for topical application
title_fullStr Preparation and evaluation pumpkin seed oil-based vitamin e cream formulations for topical application
title_full_unstemmed Preparation and evaluation pumpkin seed oil-based vitamin e cream formulations for topical application
title_sort preparation and evaluation pumpkin seed oil-based vitamin e cream formulations for topical application
publisher Japan Oil Chemists’ Society
publishDate 2020
url http://psasir.upm.edu.my/id/eprint/86667/1/Preparation%20and%20evaluation%20pumpkin%20seed%20.pdf
http://psasir.upm.edu.my/id/eprint/86667/
https://www.jstage.jst.go.jp/article/jos/69/4/69_ess19250/_article
_version_ 1724075470606041088