Mikania micrantha extract inhibits HMG-CoA reductase and ACAT2 and ameliorates hypercholesterolemia and lipid peroxidation in high cholesterol-fed rats

• Main Authors: Ibrahim, Azlinda, Shafie, Nurul Husna, Mohd Esa, Norhaizan, Shafie, Siti Raihanah, Bahari, Hasnah, Abdullah, Maizaton Atmadini
• Format: Article
• Language: English
• Published: Multidisciplinary Digital Publishing Institute 2020
• Online Access: http://psasir.upm.edu.my/id/eprint/86762/1/Mikania%20micrantha.pdf; http://psasir.upm.edu.my/id/eprint/86762/; https://www.mdpi.com/2072-6643/12/10/3077
• Institution: Universiti Putra Malaysia

The present study aimed to determine the effect of an ethyl acetate extract of Mikania micrantha stems (EAMMS) in hypercholesterolemia-induced rats. Rats were divided into a normal group (NC) and hypercholesterolemia induced groups: hypercholesterolemia control group (PC), simvastatin group (SV) (10...