Effect of combination therapy of ruthenium polypyridyl complex, [Ru(dppz)2(PIP)]2+ and parp inhibitors against several cancer cell lines

• Main Author: Yusoh, Nur Aininie
• Format: Thesis
• Language: English
• Published: 2020
• Subjects: Cancer cells - Effect of drugs on; Antineoplastic agents
• Online Access: http://psasir.upm.edu.my/id/eprint/91952/1/FS%202020%2023%20-%20IR.pdf; http://psasir.upm.edu.my/id/eprint/91952/
• Institution: Universiti Putra Malaysia

Ruthenium polypyridyl complexes (RPCs) have been clinically studied as promising anticancer agents in the last decades. The RPC, [Ru(dppz)2(PIP)]2+ or RuPIP where dppz = dipyrido[3,2-a:2’,3’-c]phenazine and PIP = 2-(pheny)- imidazo[4,5-f][1,10]phenantroline has demonstrated anticancer properties...