Surface peptide functionalization of zeolitic imidazolate framework-8 for autonomous homing and enhanced delivery of chemotherapeutic agent to lung tumor cells

• Main Authors: Mohd Abdul Kamal, Nurul Akmarina, Abdulmalek, Emilia, Fakurazi, Sharida, Cordova, Kyle E., Abdul Rahman, Mohd Basyaruddin
• Format: Article
• Published: Royal Society of Chemistry 2021
• Online Access: http://psasir.upm.edu.my/id/eprint/95219/; https://pubs.rsc.org/en/content/articlelanding/2021/dt/d1dt00116g
• Institution: Universiti Putra Malaysia

Chemotherapeutic agents used in treating certain cancer types operate in a non-selective manner tending to accumulate in normal, healthy tissue when high doses are used. To mitigate the toxicity effect resulting from this, there is an urgent need to develop active nano delivery systems capable of re...