Synthesis of new 1,2-disubstituted benzimidazole analogs as potent inhibitors of Î-Glucuronidase and in silico study

Synthesis of new 1,2-disubstituted benzimidazole analogs as potent inhibitors of Î-Glucuronidase and in silico study

New benzimidazole analogues (1–18) were synthesized and characterized through different spectroscopic techniques such as 1H NMR, 13C NMR and HREI-MS. All analogues were screened for β-glucuronidase inhibitory potential. All analogues showed varied degree of inhibitory potentials with IC50 values ran...

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Main Authors: Muhammad Taha, Ahmad Khan, Aftab, Rahim, Fazal, Imran, Syahrul, Mohammed Salahuddin, Uddin, Nizam, Mohammed Khan, Khalid, Ali Shah, Syed Adnan, Zafar, Ameeduzzafar, Zakaria, Zainul Amiruddin
Format: Article
Published: Elsevier B.V. 2021
Online Access:http://psasir.upm.edu.my/id/eprint/95271/
https://www.sciencedirect.com/science/article/pii/S1878535221005207?via%3Dihub
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Institution: Universiti Putra Malaysia

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http://psasir.upm.edu.my/id/eprint/95271/
https://www.sciencedirect.com/science/article/pii/S1878535221005207?via%3Dihub

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