Could we address the interplay between CD133, Wnt/β-Catenin, and TERT signaling pathways as a potential target for Glioblastoma therapy?
Glioblastoma multiforme (GBM) is one of the most lethal forms of primary brain tumors. Glioblastoma stem cells (GSCs) play an undeniable role in tumor development by activating multiple signaling pathways such as Wnt/β-catenin and PI3K/AKT/mTOR that facilitate brain tumor formation. CD133, a transme...
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| Main Authors: | , |
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| Format: | Article |
| Published: |
Frontiers Media
2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/96552/ https://www.frontiersin.org/articles/10.3389/fonc.2021.642719/full |
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| Institution: | Universiti Putra Malaysia |