Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber
We presented a development of a custom lead shield and mouse strainer for targeted irradiation from the gamma-cell chamber. This study was divided into two parts i.e., to (i) fabricate the shield and strainer from a lead (Pb) and (ii) optimize the irradiation to the mice-bearing tumour model with 2...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing
2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/96695/1/ABSTRACT.pdf http://psasir.upm.edu.my/id/eprint/96695/ https://www.nature.com/articles/s41598-021-93964-5 |
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| Institution: | Universiti Putra Malaysia |
| Language: | English |
| Summary: | We presented a development of a custom lead shield and mouse strainer for targeted irradiation from the gamma-cell chamber. This study was divided into two parts i.e., to (i) fabricate the shield and strainer from a lead (Pb) and (ii) optimize the irradiation to the mice-bearing tumour model with 2 and 8 Gy absorbed doses. The lead shielding was fabricated into a cuboid shape with a canal on the top and a hole on the vertical side for the beam path. Respective deliveries doses of 28 and 75 Gy from gamma-cell were used to achieve 2 and 8 Gy absorbed doses at the tumour sites. |
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