Human amniotic membrane as a homograft material in myringoplasty

• Main Author: Dalip Singh, Harvinder Singh
• Format: Thesis
• Language: English
• Published: 2001
• Subjects: RF Otorhinolaryngology
• Online Access: http://eprints.usm.my/36104/1/dr_harvinder_singh__MRM_%28NN11%2924.pdf; http://eprints.usm.my/36104/
• Institution: Universiti Sains Malaysia

Kajian ini bertujuan menilai keupayaan graf amniotic membran manusia sebagai graf alternatif dari segi struktur anatomi dan fungsi untuk menutup gegendang telinga berlubang semasa pembedahan myringoplasty. Kita juga membandingkannya dengan graf fascia temporal man usia. Kajian prospektif ini telah melibatkan seramai 50 kes yang telah dibedah bagi gegendang telinga berlubang di Hospital Universiti Sains Malaysia dari Jun 1999 sehingga Jun 2001. Dua puluh kes melibatkan penggunaan amniotic membran manusia dan 30 kes seterusnya mengunakan fascia temporal manusia. Pemeriksaan klinikal dan audiometri dijalankan 3 bulan selepas tamatnya pembedahan. To evaluate the efficacy of preserved human amniotic membrane as an alternative graft material in terms of its anatomical and functional outcomes in closing tympanic membrane defects during myringoplasties. We also compared it with the standard temporal fascia graft. A prospective review of 50 cases operated for tympanic membrane defects in Hospital University Sains Malaysia from June 1999 to June 2001. Twenty cases used preserved human amniotic membrane and 30 cases used temporal fascia graft. Clinical and audiometric assessment were done 3 months postoperatively.