Comparing the expression of human DNA topoisomerase I in KM71H and X33 strains of Pichia pastoris

Human is an essential cellular enzymethat is found in all human cells. As this enzyme is upregulated in cancer cells exceedingly, it is used as a target for cancer chemotherapeutic drug development. As such, producing the in-house enzyme for the purpose to speed up the search for more cost-effecti...

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Bibliographic Details
Main Authors: Ruo, Ping Ang, Leong, Sin Teoh, Mooi, Kwai Chana, Miswan, Noorizan, Boon, Yin Khoo
Format: Article
Published: Elsevier 2016
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Online Access:http://eprints.usm.my/36835/
http://dx.doi.org/10.1016/j.ejbt.2016.01.007
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Institution: Universiti Sains Malaysia