Crystal Structures And Analysis Of 1,2,4 Triazole And Pyrazole Compounds

The purpose of this research is to study the crystal structures of some biologically and pharmacologically important 1,2,4-triazole and pyrazole compounds by single crystal X-ray crystallography method. A series of nine compounds of 1,2,4-triazole derivatives and a series of six compounds of pyrazol...

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Bibliographic Details
Main Author: Goh , Jia Hao
Format: Thesis
Language:English
Published: 2011
Subjects:
Online Access:http://eprints.usm.my/41819/1/GOH_JIA_HAO.pdf
http://eprints.usm.my/41819/
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Institution: Universiti Sains Malaysia
Language: English
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Summary:The purpose of this research is to study the crystal structures of some biologically and pharmacologically important 1,2,4-triazole and pyrazole compounds by single crystal X-ray crystallography method. A series of nine compounds of 1,2,4-triazole derivatives and a series of six compounds of pyrazole derivatives were synthesized and crystallized to obtain single crystals. The data was collected using either Bruker SMART APEXII or Bruker APEXII DUO CCD area-detector diffractometers. The structures were solved by direct methods and refined by least-squares method.