Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)

Adherence to antihypertensive medications in general is not well documented in developing countries, and what is known is far from encouraging. Despite the effectiveness of antihypertensive treatment, medication adherence is often suboptimal in hypertensive Malaysian population. This retro-pro...

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Main Author: Sundaram , Arunkumar
Format: Thesis
Language:English
Published: 2010
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Online Access:http://eprints.usm.my/42870/1/Arunkumar_Sundaram24.pdf
http://eprints.usm.my/42870/
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Institution: Universiti Sains Malaysia
Language: English
id my.usm.eprints.42870
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spelling my.usm.eprints.42870 http://eprints.usm.my/42870/ Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr) Sundaram , Arunkumar R5-130.5 General works Adherence to antihypertensive medications in general is not well documented in developing countries, and what is known is far from encouraging. Despite the effectiveness of antihypertensive treatment, medication adherence is often suboptimal in hypertensive Malaysian population. This retro-prospective cohort study aimed to assess the medication adherence, and factors affecting this. A cohort of 380 hypertensive patients was conveniently recruited from the outpatient hypertension clinic at Penang General Hospital, Malaysia. The Morisky self-report scale revealed that 51.3% patients (n=195) had poor adherence to prescribed antihypertensive medication. A Semistructured interview revealed forgetfulness due to a lack of symptoms; poor social support, medication side effects, and the perception that long-term medication may be addictive were principal factors of poor adherence to medication. The structural equation modelling (SEM), which identified the multivariate hypothesized predictors of poor adherence to medication, showed that a lack of self discipline, aversion towards medication, and a negative attitude towards medication in general negatively accounted for 75% of factors affecting medication adherence. 2010-06 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/42870/1/Arunkumar_Sundaram24.pdf Sundaram , Arunkumar (2010) Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr). Masters thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic R5-130.5 General works
spellingShingle R5-130.5 General works
Sundaram , Arunkumar
Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
description Adherence to antihypertensive medications in general is not well documented in developing countries, and what is known is far from encouraging. Despite the effectiveness of antihypertensive treatment, medication adherence is often suboptimal in hypertensive Malaysian population. This retro-prospective cohort study aimed to assess the medication adherence, and factors affecting this. A cohort of 380 hypertensive patients was conveniently recruited from the outpatient hypertension clinic at Penang General Hospital, Malaysia. The Morisky self-report scale revealed that 51.3% patients (n=195) had poor adherence to prescribed antihypertensive medication. A Semistructured interview revealed forgetfulness due to a lack of symptoms; poor social support, medication side effects, and the perception that long-term medication may be addictive were principal factors of poor adherence to medication. The structural equation modelling (SEM), which identified the multivariate hypothesized predictors of poor adherence to medication, showed that a lack of self discipline, aversion towards medication, and a negative attitude towards medication in general negatively accounted for 75% of factors affecting medication adherence.
format Thesis
author Sundaram , Arunkumar
author_facet Sundaram , Arunkumar
author_sort Sundaram , Arunkumar
title Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
title_short Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
title_full Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
title_fullStr Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
title_full_unstemmed Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
title_sort antioxidant status and the effect of tocotrienol-rich-fraction (trf) supplementation on the antioxidant enzymes and development of hypertension in spontaneously hypertensive rats (shr)
publishDate 2010
url http://eprints.usm.my/42870/1/Arunkumar_Sundaram24.pdf
http://eprints.usm.my/42870/
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