Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial

Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial

Patients with End Stage Renal Disease (ESRD) require lifelong fluid replacement therapy or renal transplant. Almost 60-90 % haemodialysis patients are hypertensive. Studies aimed at elucidating the pathophysiology of hypertension among haemodialysis patients concluded that 90% cases resulted from so...

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Main Author: Aftab, Raja Ahsan
Format: Thesis
Language:English
Published: 2018
Subjects:
RS1-441 Pharmacy and materia medica
Online Access:http://eprints.usm.my/43726/1/RAJA%20AHSAN%20AFTAB.pdf
http://eprints.usm.my/43726/
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Institution: Universiti Sains Malaysia
Language: English
id my.usm.eprints.43726
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spelling my.usm.eprints.43726 http://eprints.usm.my/43726/ Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial Aftab, Raja Ahsan RS1-441 Pharmacy and materia medica Patients with End Stage Renal Disease (ESRD) require lifelong fluid replacement therapy or renal transplant. Almost 60-90 % haemodialysis patients are hypertensive. Studies aimed at elucidating the pathophysiology of hypertension among haemodialysis patients concluded that 90% cases resulted from sodium and volume overload (volume-dependent), while the majority of the remaining cases have elevated renin activity (renin dependent), leading to renin dependent high blood pressure. Since there is a constant volume variation during dialysis session, there is a strong possibility for activation of Renin Angiotensin Aldosterone System (RAAS) during dialysis that causes high blood pressure even if they are post dialysis euvolemic. 2018-01 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/43726/1/RAJA%20AHSAN%20AFTAB.pdf Aftab, Raja Ahsan (2018) Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial. PhD thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Aftab, Raja Ahsan
Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial
description Patients with End Stage Renal Disease (ESRD) require lifelong fluid replacement therapy or renal transplant. Almost 60-90 % haemodialysis patients are hypertensive. Studies aimed at elucidating the pathophysiology of hypertension among haemodialysis patients concluded that 90% cases resulted from sodium and volume overload (volume-dependent), while the majority of the remaining cases have elevated renin activity (renin dependent), leading to renin dependent high blood pressure. Since there is a constant volume variation during dialysis session, there is a strong possibility for activation of Renin Angiotensin Aldosterone System (RAAS) during dialysis that causes high blood pressure even if they are post dialysis euvolemic.
format Thesis
author Aftab, Raja Ahsan
author_facet Aftab, Raja Ahsan
author_sort Aftab, Raja Ahsan
title Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial
title_short Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial
title_full Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial
title_fullStr Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial
title_full_unstemmed Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial
title_sort safety and efficacy of losartan (50 mg) in post dialysis euvolemic hypertensive patients: a single-blind randomized control trial
publishDate 2018
url http://eprints.usm.my/43726/1/RAJA%20AHSAN%20AFTAB.pdf
http://eprints.usm.my/43726/
_version_ 1643710818547662848

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