Association of degree of expression of ki 67 proliferative cell marker with aggressive giant cell tumor of the bone
Stag11 Ill Campanacci giant cell tumour of· the bone always exhibits high biological aggressiveness and has tendency for local recurrenc11s and pulmonary metastases. We analyzed Ki-67 immuno-histochemistry of 31 cases of stage Ill giant cell tumour of the bone to determine the clinico-pathologica...
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| Main Author: | |
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| Format: | Monograph |
| Language: | English |
| Published: |
Pusat Pengajian Sains Perubatan
2013
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| Subjects: | |
| Online Access: | http://eprints.usm.my/54873/1/DR.%20WAN%20FAISHAM%20NU%20MAN%20WAN%20ISMAIL%20-%20e.pdf http://eprints.usm.my/54873/ |
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| Institution: | Universiti Sains Malaysia |
| Language: | English |
| Summary: | Stag11 Ill Campanacci giant cell tumour of· the bone always exhibits high
biological aggressiveness and has tendency for local recurrenc11s and pulmonary
metastases. We analyzed Ki-67 immuno-histochemistry of 31 cases of stage Ill
giant cell tumour of the bone to determine the clinico-pathological correlation.
The mean value of Ki-67 index obtained as a percentage of 1000 background
cells was 8. 15 with range from 1. 00 to 20. 00. There was no difference of indices
in cases with r11currence and pulmonary metastasis. In conclusion, Ki-67 index is
not useful as a prognostic marker for aggressive typ.e of giant cell tumour of the
bone. |
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