Synthesis, Characterization Of 1,3-Diarylpropenes And Tricyclic Indolines And The Cytotoxic Activities Of 1,3-Diarylpropenes
Alkaloids are crucial nitrogen-containing compounds that exhibit diverse biological and pharmaceutical activity, regardless of the compound scaffold. Accordingly, it drives the synthesis of amido 1,3-diarylpropene and 6-5-4 tricyclic indoline under the alkaloid class, potentially the chemotherapeut...
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| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
2022
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| Subjects: | |
| Online Access: | http://eprints.usm.my/59746/1/Pages%20from%20TAN%20AIK%20SIAN%20-%20TESIS.pdf http://eprints.usm.my/59746/ |
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| Institution: | Universiti Sains Malaysia |
| Language: | English |
| Summary: | Alkaloids are crucial nitrogen-containing compounds that exhibit diverse biological and pharmaceutical activity, regardless of the compound scaffold. Accordingly, it drives the synthesis of amido 1,3-diarylpropene and 6-5-4 tricyclic
indoline under the alkaloid class, potentially the chemotherapeutic agents for cancer treatment. In the first study, forty (40) 1,3-diarylpropene derivatives, designed
analogs of stilbenoids and dihydrostilbenoids, were synthesized by the palladiumcatalyzed reactions of 2-amidoiodobenzene derivatives with either estragole or
eugenol. |
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