Effect Of Gelucire 44/14 On The Oral Bioavailability Of Cyclosporin A [RM666.C978 L73 2007 f rb ].
Kajian ini dijalankan untuk mengkaji kesan Gelucire® 44/14 terhadap biokeperolehan oral bagi satu drug polipeptida lipofilik model, ciclosporin A. Formulasi Gelucire® 44/14 mengandungi ciclosporin A dengan nisbah drug kepada Gelucire® 44/14 1:4, 1:10, 1:14 dan 1:20 telah berjaya disediakan melalui t...
Saved in:
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2007
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/8135/1/EFFECT_OF_GELUCIRE_44_14_ON_THE_ORAL_BIOAVAILABILITY_OF_CYCLOSPORIN_A.pdf http://eprints.usm.my/8135/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Universiti Sains Malaysia |
| Language: | English |
| Summary: | Kajian ini dijalankan untuk mengkaji kesan Gelucire® 44/14 terhadap biokeperolehan oral bagi satu drug polipeptida lipofilik model, ciclosporin A. Formulasi Gelucire® 44/14 mengandungi ciclosporin A dengan nisbah drug kepada Gelucire® 44/14 1:4, 1:10, 1:14 dan 1:20 telah berjaya disediakan melalui teknik lebur-fusi.
The present study was conducted to investigate the effect of Gelucire® 44/14 on the oral bioavailability of a model lipophilic polypeptide drug, cyclosporin A. Gelucire® 44/14 formulations of cyclosporin A at drug to Gelucire® 44/14 ratios of 1:4, 1:10, 1:14 and 1:20 (w/w) were successfully prepared using a heatfusion method. |
|---|