Enhancement of MCF-7 and HeLa Cell interfacial interactions using pulse electric field and natural sustainable resources

• Main Authors: Ganeson, Suhassni, Abdul Jamil, Muhammad Mahadi, Ambar, Radzi, Wan Zaki, Wan Suhaimizan, Abd Wahab, Mohd Helmy, Marimuthu, Shamala, Abd Rahman, Nur Adilah, Mamman, Hassan Buhari
• Format: Conference or Workshop Item
• Language: English
• Published: 2024
• Subjects: T Technology (General)
• Online Access: http://eprints.uthm.edu.my/11943/1/Enhancement%20of%20MCF-7.pdf; http://eprints.uthm.edu.my/11943/; https://doi.org/10.1016/j.procs.2024.05.033
• Institution: Universiti Tun Hussein Onn Malaysia

Electroporation plays a part in chemotherapy, providing a promising strategy to increase the potency of anticancer medications and enhance treatment outcomes in some types of malignancies. Electroporation is a biological technique in which short electrical impulses are applied to cells or tissues, which temporarily destroying their cell membranes. This disruption creates temporary pores or channels in the cell membrane, allowing for the introduction of membrane that allow foreign substances such as DNA, RNA, proteins, proteins, or drugs into to enter the cells. The effectiveness of the technique will aid in the development of new cancer cell therapies and wound healing approaches. This review addresses the effects of electroporation techniques on breast cancer cells (MCF-7) and cervical cancer cell (Hela) using electric pulse ranging from 100-100V/cm. On top of that, honey extracts will be injected into breast cancer cells and cervical cancer cells using electrical pulses or the electroporation technique to examine the anti-cancer mechanism. This research finding may lead to fewer adverse effects of cancer treatment while maintaining patients' health and enhancing overall life expectancy.