Nanodiamond conjugated SARS-CoV-2 spike protein: electrochemical impedance immunosensing on a gold microelectrode

• Main Authors: Ramanathan, Santheraleka, Gopinath, Subash C. B., Ismail, Zool Hilmi, Subramaniam, Sreeramanan
• Format: Article
• Language: English
• Published: Springer Nature 2022
• Subjects: Q Science (General); TK Electrical engineering. Electronics Nuclear engineering; TP Chemical technology
• Online Access: http://eprints.utm.my/103293/1/ZoolHilmiIsmail2022_NanodiamondConjugatedSARSCoV2SpikeProtein.pdf; http://eprints.utm.my/103293/; http://dx.doi.org/10.1007/s00604-022-05320-7
• Institution: Universiti Teknologi Malaysia

A promising immunosensing strategy in diagnosing SARS-CoV-2 is proposed using a 10-µm gap-sized gold interdigitated electrode (AuIDE) to target the surface spike protein (SP). The microelectrode surface was modified by (3-glycidyloxypropyl) trimethoxysilane to enforce the epoxy matrix, which facilit...