Differential correlations informed metabolite set enrichment analysis to decipher metabolic heterogeneity of disease

Metabolic pathways are regarded as functional and basic components of the biological system. In metabolomics, metabolite set enrichment analysis (MSEA) is often used to identify the altered metabolic pathways (metabolite sets) associated with phenotypes of interest (POI), e.g., disease. However, in...

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Bibliographic Details
Main Authors: Lin, Genjin, Dong, Liheng, Cheng, Kian-Kai, Xu, Xiangnan, Wang, Yongpei, Deng, Lingli, Raftery, Daniel, Dong, Jiyang
Format: Article
Published: American Chemical Society 2023
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Online Access:http://eprints.utm.my/105022/
http://dx.doi.org/10.1021/acs.analchem.3c02246
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Institution: Universiti Teknologi Malaysia