Neuroprotective effects of exogenous brain-derived neurotrophic factor on amyloid-beta 1-40-induced retinal degeneration

• Main Authors: Mohd. Lazaldin, Mohd. Aizuddin, Iezhitsa, Igor, Agarwal, Renu, Agarwal, Puneet, Mohd. Ismail, Nafeeza
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2023
• Subjects: Q Science (General)
• Online Access: http://eprints.utm.my/106032/1/MohdAizuddinMohd2023_NeuroprotectiveEffectsofExogenousBrainDerived.pdf; http://eprints.utm.my/106032/; http://dx.doi.org/10.4103/1673-5374.346546
• Institution: Universiti Teknologi Malaysia

Amyloid-beta (Aβ)-related alterations, similar to those found in the brains of patients with Alzheimer's disease, have been observed in the retina of patients with glaucoma. Decreased levels of brain-derived neurotrophic factor (BDNF) are believed to be associated with the neurotoxic effects of...