Overview of repressive miRNA regulation by Short Tandem Target Mimic (STTM): applications and impact on plant biology

• Main Authors: Syed Othman, Syed Muhammad Iqbal, Mustaffa, Arif Faisal, Che Othman, M. Hafiz, A. Samad, Abdul Fatah, Goh, Hoe Han, Zainal, Zamri, Ismail, Ismanizan
• Format: Article
• Language: English
• Published: MDPI 2023
• Subjects: Q Science (General)
• Online Access: http://eprints.utm.my/106368/1/AbdulFatahA2023_OverviewofRepressivemiRNARegulationbyShort.pdf; http://eprints.utm.my/106368/; http://dx.doi.org/10.3390/plants12030669
• Institution: Universiti Teknologi Malaysia

The application of miRNA mimic technology for silencing mature miRNA began in 2007. This technique originated from the discovery of the INDUCED BY PHOSPHATE STARVATION 1 (IPS1) gene, which was found to be a competitive mimic that prevents the cleavage of the targeted mRNA by miRNA inhibition at the...