Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: a review of common approaches

• Main Authors: Misman, Muhammad Faiz, Deris, Safaai, Mohd. Hashim, Siti Zaiton, Jumali, R., Mohamad, Mohd. Saberi
• Format: Book Section
• Published: Institute of Electrical and Electronics Engineers 2009
• Subjects: QA75 Electronic computers. Computer science
• Online Access: http://eprints.utm.my/id/eprint/13040/; http://dx.doi.org/10.1109/ICIME.2009.103
• Institution: Universiti Teknologi Malaysia

In this reiew, we have discussed about approaches in pathway based microarray analysis. Commonly, there are two approaches in pathway based analysis, Enrichment Score and Supervised Machine Learning. These pathway based approaches usually aim to statistically define significant pathways that related...