Metabolomics of the interaction between PPAR-? and age in the PPAR-?-null mouse

• Main Authors: Atherton, Helen J., Gulston, Melanie K., Bailey, Nigel J., Cheng, Kian-Kai, Zhang, Wen, Clarke, Kieran, Griffin, Julian L.
• Format: Article
• Published: 2009
• Subjects: Q Science (General); T Technology (General)
• Online Access: http://eprints.utm.my/id/eprint/13208/; http://dx.doi.org/10.1038/msb.2009.18
• Institution: Universiti Teknologi Malaysia

Regulation between the fed and fasted states in mammals is partially controlled by peroxisome proliferator-activated receptor-alpha (PPAR-alpha). Expression of the receptor is high in tissues with a high catabolic rate such as the liver, heart and skeletal muscle, and its activation results in the d...