Chiral separation of econazole using micellar electrokinetic chromatography with hydroxypropyl-gamma-cyclodextrin

The separation of enantiomers is one of the important fi elds of modern analytical chemistry, especially for agrochemical and pharmaceutical products because the stereochemistry has a signi fi cant in fl uence on the biological activities of compounds. Cyclodextrin-modi fi ed micellar electrokinetic...

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Main Authors:	Ibrahim, W. A. W., Hermawan, Dadan, Sanagi, M. M.
Format:	Article
Published:	Elsevier B. V. 2010
Subjects:	Q Science (General)
Online Access:	http://eprints.utm.my/id/eprint/22959/ http://dx.doi.org/10.1007/978-1-62703-263-6_22
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Institution:	Universiti Teknologi Malaysia

id	my.utm.22959
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spelling	my.utm.229592018-10-21T04:29:50Z http://eprints.utm.my/id/eprint/22959/ Chiral separation of econazole using micellar electrokinetic chromatography with hydroxypropyl-gamma-cyclodextrin Ibrahim, W. A. W. Hermawan, Dadan Sanagi, M. M. Q Science (General) The separation of enantiomers is one of the important fi elds of modern analytical chemistry, especially for agrochemical and pharmaceutical products because the stereochemistry has a signi fi cant in fl uence on the biological activities of compounds. Cyclodextrin-modi fi ed micellar electrokinetic chromatography (CD-MEKC) has become an important capillary electrophoresis mode for enantioseparations. Here, we describe an example of a CD-MEKC method using hydroxypropyl- ? -cyclodextrin as chiral selector and sodium dodecyl sulfate as micellar solution for enantioseparation of triazole fungicides and the drug econazole. Elsevier B. V. 2010-12 Article PeerReviewed Ibrahim, W. A. W. and Hermawan, Dadan and Sanagi, M. M. (2010) Chiral separation of econazole using micellar electrokinetic chromatography with hydroxypropyl-gamma-cyclodextrin. Journal of Pharmaceutical and Biomedical Analysis, 53 (5). 1244 - 1249. http://dx.doi.org/10.1007/978-1-62703-263-6_22 DOI:10.1007/978-1-62703-263-6_22
institution	Universiti Teknologi Malaysia
building	UTM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Teknologi Malaysia
content_source	UTM Institutional Repository
url_provider	http://eprints.utm.my/
topic	Q Science (General)
spellingShingle	Q Science (General) Ibrahim, W. A. W. Hermawan, Dadan Sanagi, M. M. Chiral separation of econazole using micellar electrokinetic chromatography with hydroxypropyl-gamma-cyclodextrin
description	The separation of enantiomers is one of the important fi elds of modern analytical chemistry, especially for agrochemical and pharmaceutical products because the stereochemistry has a signi fi cant in fl uence on the biological activities of compounds. Cyclodextrin-modi fi ed micellar electrokinetic chromatography (CD-MEKC) has become an important capillary electrophoresis mode for enantioseparations. Here, we describe an example of a CD-MEKC method using hydroxypropyl- ? -cyclodextrin as chiral selector and sodium dodecyl sulfate as micellar solution for enantioseparation of triazole fungicides and the drug econazole.
format	Article
author	Ibrahim, W. A. W. Hermawan, Dadan Sanagi, M. M.
author_facet	Ibrahim, W. A. W. Hermawan, Dadan Sanagi, M. M.
author_sort	Ibrahim, W. A. W.
title	Chiral separation of econazole using micellar electrokinetic chromatography with hydroxypropyl-gamma-cyclodextrin
title_short	Chiral separation of econazole using micellar electrokinetic chromatography with hydroxypropyl-gamma-cyclodextrin
title_full	Chiral separation of econazole using micellar electrokinetic chromatography with hydroxypropyl-gamma-cyclodextrin
title_fullStr	Chiral separation of econazole using micellar electrokinetic chromatography with hydroxypropyl-gamma-cyclodextrin
title_full_unstemmed	Chiral separation of econazole using micellar electrokinetic chromatography with hydroxypropyl-gamma-cyclodextrin
title_sort	chiral separation of econazole using micellar electrokinetic chromatography with hydroxypropyl-gamma-cyclodextrin
publisher	Elsevier B. V.
publishDate	2010
url	http://eprints.utm.my/id/eprint/22959/ http://dx.doi.org/10.1007/978-1-62703-263-6_22
_version_	1643647434965909504

Chiral separation of econazole using micellar electrokinetic chromatography with hydroxypropyl-gamma-cyclodextrin

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