Metabolomic study of the LDL receptor null mouse fed a high-fat diet reveals profound perturbations in choline metabolism that are shared with ApoE null mice

Metabolomic study of the LDL receptor null mouse fed a high-fat diet reveals profound perturbations in choline metabolism that are shared with ApoE null mice

Failure to express or expression of dysfunctional low-density lipoprotein receptors (LDLR) causes familial hypercholesterolemia in humans, a disease characterized by elevated blood cholesterol concentrations, xanthomas, and coronary heart disease, providing compelling evidence that high blood choles...

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Main Authors: Kian Kai, Cheng, Benson, G. Martin, C. Grimsditch, David, G. Reid, David, C. Connor, Susan, L. Griffin, Julian
Format: Article
Language:English
Published: The American Physiological Society 2010
Subjects:
QD Chemistry
Online Access:http://eprints.utm.my/id/eprint/26274/1/ChengKianKai2010_MetabolomicStudyoftheLDLReceptorNull.pdf
http://eprints.utm.my/id/eprint/26274/
http://dx.doi.org/10.1152/physiolgenomics.00188.2009
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Institution: Universiti Teknologi Malaysia
Language: English

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http://eprints.utm.my/id/eprint/26274/1/ChengKianKai2010_MetabolomicStudyoftheLDLReceptorNull.pdf
http://eprints.utm.my/id/eprint/26274/
http://dx.doi.org/10.1152/physiolgenomics.00188.2009

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