Covalent immobilization of penicillin g acylase onto chemically activated surface of poly(vinyl chloride) membranes for 6-penicillic acid production from penicillin hydrolysis process i. Optimization of surface modification and its characterization

• Main Authors: Eldin, M. S. M., El Enshasy, H. A., El Sayed, M., El Sayed, S., Haroun, B., Hassan, E. A.
• Format: Article
• Published: Wiley Periodicals 2012
• Subjects: TA Engineering (General). Civil engineering (General)
• Online Access: http://eprints.utm.my/id/eprint/46750/; https://dx.doi.org/10.1002/app.35390
• Institution: Universiti Teknologi Malaysia

The covalent immobilization of penicillin G acylase (PGA) onto the surface of NH2–poly(vinyl chloride) (PVC) membranes was studied. PGA was chosen because it plays a relevant role in the pharmaceutical industry, catalyzing the production of an important intermediate for the industrial production of...