Permeability study of cancellous bone and its idealised structures

Artificial bone is a suitable alternative to autografts and allografts, however their use is still limited. Though there were numerous reports on their structural properties, permeability studies of artificial bones were comparably scarce. This study focused on the development of idealised, structur...

Full description

Saved in:
Bibliographic Details
Main Authors: Syahrom, Ardiyansyah, Abdul Kadir, Mohammed Rafiq, Harun, Muhamad Nor, Ochsner, Andreas
Format: Article
Published: Elsevier Ltd 2015
Subjects:
Online Access:http://eprints.utm.my/id/eprint/58810/
http://dx.doi.org/10.1016/j.medengphy.2014.11.001
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Universiti Teknologi Malaysia
Description
Summary:Artificial bone is a suitable alternative to autografts and allografts, however their use is still limited. Though there were numerous reports on their structural properties, permeability studies of artificial bones were comparably scarce. This study focused on the development of idealised, structured models of artificial cancellous bone and compared their permeability values with bone surface area and porosity. Cancellous bones from fresh bovine femur were extracted and cleaned following an established protocol. The samples were scanned using micro-computed tomography (μCT) and three-dimensional models of the cancellous bones were reconstructed for morphology study. Seven idealised and structured cancellous bone models were then developed and fabricated via rapid prototyping technique. A test-rig was developed and permeability tests were performed on the artificial and real cancellous bones. The results showed a linear correlation between the permeability and the porosity as well as the bone surface area. The plate-like idealised structure showed a similar value of permeability to the real cancellous bones.