Sustainable alternative protocols for the multicomponent synthesis of spiro-4H-pyrans catalyzed by 4-dimethylaminopyridine

Sustainable alternative protocols for the multicomponent synthesis of spiro-4H-pyrans catalyzed by 4-dimethylaminopyridine

Green approaches to the synthesis of spiro-4. H-pyrans are reported based on the one-pot and three-component condensation via a domino Knoevenagel/Michael/cyclization sequence. These approaches involve evaluation of the activity of several organocatalysts in water as a reaction media and also under...

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Main Authors: Zakeri, Masoumeh, Nasef, Mohamed Mahmoud, Abouzari-Lotf, Ebrahim, Moharami, Arezoo, Heravi, Majid M.
Format: Article
Published: Korean Society of Industrial Engineering Chemistry 2015
Subjects:
QD Chemistry
TP Chemical technology
Online Access:http://eprints.utm.my/id/eprint/58847/
http://dx.doi.org/10.1016/j.jiec.2015.03.035
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Institution: Universiti Teknologi Malaysia
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spelling my.utm.588472021-12-19T03:26:50Z http://eprints.utm.my/id/eprint/58847/ Sustainable alternative protocols for the multicomponent synthesis of spiro-4H-pyrans catalyzed by 4-dimethylaminopyridine Zakeri, Masoumeh Nasef, Mohamed Mahmoud Abouzari-Lotf, Ebrahim Moharami, Arezoo Heravi, Majid M. QD Chemistry TP Chemical technology Green approaches to the synthesis of spiro-4. H-pyrans are reported based on the one-pot and three-component condensation via a domino Knoevenagel/Michael/cyclization sequence. These approaches involve evaluation of the activity of several organocatalysts in water as a reaction media and also under solvent-free in both microwave irradiation and ball milling conditions. Extensive experiments were carried out to optimize the reaction parameters including type and amount of catalyst, reaction temperature and time. Microwave irradiation in presence of 4-dimethylaminopyridine (DMAP) was observed as the best procedure with good yields, short reaction time, environmental friendliness, and convenient operation. Korean Society of Industrial Engineering Chemistry 2015-09-25 Article PeerReviewed Zakeri, Masoumeh and Nasef, Mohamed Mahmoud and Abouzari-Lotf, Ebrahim and Moharami, Arezoo and Heravi, Majid M. (2015) Sustainable alternative protocols for the multicomponent synthesis of spiro-4H-pyrans catalyzed by 4-dimethylaminopyridine. Journal of Industrial and Engineering Chemistry, 29 . pp. 273-281. ISSN 1226-086X http://dx.doi.org/10.1016/j.jiec.2015.03.035 DOI:10.1016/j.jiec.2015.03.035
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic QD Chemistry
TP Chemical technology
spellingShingle QD Chemistry
TP Chemical technology
Zakeri, Masoumeh
Nasef, Mohamed Mahmoud
Abouzari-Lotf, Ebrahim
Moharami, Arezoo
Heravi, Majid M.
Sustainable alternative protocols for the multicomponent synthesis of spiro-4H-pyrans catalyzed by 4-dimethylaminopyridine
description Green approaches to the synthesis of spiro-4. H-pyrans are reported based on the one-pot and three-component condensation via a domino Knoevenagel/Michael/cyclization sequence. These approaches involve evaluation of the activity of several organocatalysts in water as a reaction media and also under solvent-free in both microwave irradiation and ball milling conditions. Extensive experiments were carried out to optimize the reaction parameters including type and amount of catalyst, reaction temperature and time. Microwave irradiation in presence of 4-dimethylaminopyridine (DMAP) was observed as the best procedure with good yields, short reaction time, environmental friendliness, and convenient operation.
format Article
author Zakeri, Masoumeh
Nasef, Mohamed Mahmoud
Abouzari-Lotf, Ebrahim
Moharami, Arezoo
Heravi, Majid M.
author_facet Zakeri, Masoumeh
Nasef, Mohamed Mahmoud
Abouzari-Lotf, Ebrahim
Moharami, Arezoo
Heravi, Majid M.
author_sort Zakeri, Masoumeh
title Sustainable alternative protocols for the multicomponent synthesis of spiro-4H-pyrans catalyzed by 4-dimethylaminopyridine
title_short Sustainable alternative protocols for the multicomponent synthesis of spiro-4H-pyrans catalyzed by 4-dimethylaminopyridine
title_full Sustainable alternative protocols for the multicomponent synthesis of spiro-4H-pyrans catalyzed by 4-dimethylaminopyridine
title_fullStr Sustainable alternative protocols for the multicomponent synthesis of spiro-4H-pyrans catalyzed by 4-dimethylaminopyridine
title_full_unstemmed Sustainable alternative protocols for the multicomponent synthesis of spiro-4H-pyrans catalyzed by 4-dimethylaminopyridine
title_sort sustainable alternative protocols for the multicomponent synthesis of spiro-4h-pyrans catalyzed by 4-dimethylaminopyridine
publisher Korean Society of Industrial Engineering Chemistry
publishDate 2015
url http://eprints.utm.my/id/eprint/58847/
http://dx.doi.org/10.1016/j.jiec.2015.03.035
_version_ 1720436891984068608

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