Structure prediction of stem bromelain from pineapples (Ananas comosus) using procaricain enzyme as a modelling template

• Main Authors: Tap, F. M., Majid, F. A. A., Khairudin, N. B. A.
• Format: Article
• Published: Research India Publications 2016
• Subjects: TA Engineering (General). Civil engineering (General)
• Online Access: http://eprints.utm.my/id/eprint/71686/; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026750899&partnerID=40&md5=fb7e7d0e467f3f18562a025b5f60330b
• Institution: Universiti Teknologi Malaysia

Bromelain is a general name for a family of sulfhydryl that can be found in the proteolytic enzyme group from pineapples (Ananas Comosus). In this study focuses on the prediction of three dimensional structure (3D) of bromelain using homology modelling by MODELLER. The amino acid sequence of bromelain was obtained from the NCBI database and the analysis was done using various bioinformatics tools. 1PCI was used as the target templates for bromelain structure prediction. The 1PCI was found to be the most suitable template for the prediction of the bromelain structure.