Utilization of the ability to induce activation of the nuclear factor (erythroid-derived 2)-like factor 2 (Nrf2) to assess potential cancer chemopreventive activity of liquorice samples

• Main Authors: Basar, N., Nahar, L., Oridupa, O. A., Ritchie, K. J., Talukdar, A. D., Stafford, A., Kushiev, H., Kan, A., Sarker, S. D.
• Format: Article
• Published: John Wiley and Sons Ltd 2016
• Subjects: QD Chemistry
• Online Access: http://eprints.utm.my/id/eprint/72179/; https://www.scopus.com/inward/record.uri?eid=2-s2.0-84982224710&doi=10.1002%2fpca.2616&partnerID=40&md5=9b002d93328eef2ca69d251110b56767
• Institution: Universiti Teknologi Malaysia

Introduction: Nuclear factor (erythroid-derived 2)-like factor 2 (Nrf2) is a transcription factor that regulates expression of many detoxification enzymes. Nrf2-antioxidant responsive element (Nrf2-ARE) signalling pathway can be a target for cancer chemoprevention. Glycyrrhiza glabra, common name, ‘...