A new prenylated dihydrochalcone from the leaves of Artocarpus lowii

• Main Authors: Jamil, Shajarahtunnur, Sirat, Hasnah Mohd, Jantan, Jantan, Aimi, Norio, Kitajima, Mariko
• Format: Article
• Language: English
• Published: Springer 2008
• Subjects: RV Botanic, Thomsonian, and eclectic medicine
• Online Access: http://eprints.utm.my/id/eprint/7431/3/SiratHasnah2008_NewPrenylatedDihydrochalconeLeavesArtocarpus.pdf; http://eprints.utm.my/id/eprint/7431/; http://dx.doi.org/10.1007/s11418-008-0226-3
• Institution: Universiti Teknologi Malaysia

A new prenylated dihydrochalcone, 2′,4′-dihydroxy-4-methoxy-3′-prenyldihydrochalcone (1), along with two known compounds, 2′,4′,4-trihydroxy-3′-prenylchalcone (2) and 2′,4-dihydroxy-3′,4′-(2,2-dimethylchromene)chalcone (3) were isolated from the leaves of Artocarpus lowii. The structures of 1-3 were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compounds 1-3 showed strong free radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl (DPPH) measured by electron spin resonance (ESR) spectrometry.