Synthesis, characterization, antifungal activities and crystal structure of thiophene-based heterocyclic chalcones

Synthesis, characterization, antifungal activities and crystal structure of thiophene-based heterocyclic chalcones

Heterocyclic chalcones containing thiophene moiety were synthesized and their chemical structures determined via IR, MS, 1H NMR and 13C NMR spectroscopy. Crystal structure of the compounds was determined using single crystal X-ray diffraction.The chalcones were also screened for in-vitro antifungal...

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Main Authors: Ming, L. S., Jamalis, J., Al Maqtari, H. M., Rosli, M. M., Sankaranarayanan, M., Chander, S., Fun, H. K.
Format: Article
Published: Elsevier B.V. 2017
Subjects:
QD Chemistry
Online Access:http://eprints.utm.my/id/eprint/75480/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018957104&doi=10.1016%2fj.cdc.2017.04.004&partnerID=40&md5=04d8ce2afc200329b1527e2012ce8673
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Institution: Universiti Teknologi Malaysia
id my.utm.75480
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spelling my.utm.754802018-03-28T04:05:23Z http://eprints.utm.my/id/eprint/75480/ Synthesis, characterization, antifungal activities and crystal structure of thiophene-based heterocyclic chalcones Ming, L. S. Jamalis, J. Al Maqtari, H. M. Rosli, M. M. Sankaranarayanan, M. Chander, S. Fun, H. K. QD Chemistry Heterocyclic chalcones containing thiophene moiety were synthesized and their chemical structures determined via IR, MS, 1H NMR and 13C NMR spectroscopy. Crystal structure of the compounds was determined using single crystal X-ray diffraction.The chalcones were also screened for in-vitro antifungal activity against two fungal strains; Candida albicans (MTCC 3958) and Aspergillus niger (MTCC 9933)which gave good results. Elsevier B.V. 2017 Article PeerReviewed Ming, L. S. and Jamalis, J. and Al Maqtari, H. M. and Rosli, M. M. and Sankaranarayanan, M. and Chander, S. and Fun, H. K. (2017) Synthesis, characterization, antifungal activities and crystal structure of thiophene-based heterocyclic chalcones. Chemical Data Collections, 9-10 . pp. 104-113. ISSN 2405-8300 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018957104&doi=10.1016%2fj.cdc.2017.04.004&partnerID=40&md5=04d8ce2afc200329b1527e2012ce8673
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic QD Chemistry
spellingShingle QD Chemistry
Ming, L. S.
Jamalis, J.
Al Maqtari, H. M.
Rosli, M. M.
Sankaranarayanan, M.
Chander, S.
Fun, H. K.
Synthesis, characterization, antifungal activities and crystal structure of thiophene-based heterocyclic chalcones
description Heterocyclic chalcones containing thiophene moiety were synthesized and their chemical structures determined via IR, MS, 1H NMR and 13C NMR spectroscopy. Crystal structure of the compounds was determined using single crystal X-ray diffraction.The chalcones were also screened for in-vitro antifungal activity against two fungal strains; Candida albicans (MTCC 3958) and Aspergillus niger (MTCC 9933)which gave good results.
format Article
author Ming, L. S.
Jamalis, J.
Al Maqtari, H. M.
Rosli, M. M.
Sankaranarayanan, M.
Chander, S.
Fun, H. K.
author_facet Ming, L. S.
Jamalis, J.
Al Maqtari, H. M.
Rosli, M. M.
Sankaranarayanan, M.
Chander, S.
Fun, H. K.
author_sort Ming, L. S.
title Synthesis, characterization, antifungal activities and crystal structure of thiophene-based heterocyclic chalcones
title_short Synthesis, characterization, antifungal activities and crystal structure of thiophene-based heterocyclic chalcones
title_full Synthesis, characterization, antifungal activities and crystal structure of thiophene-based heterocyclic chalcones
title_fullStr Synthesis, characterization, antifungal activities and crystal structure of thiophene-based heterocyclic chalcones
title_full_unstemmed Synthesis, characterization, antifungal activities and crystal structure of thiophene-based heterocyclic chalcones
title_sort synthesis, characterization, antifungal activities and crystal structure of thiophene-based heterocyclic chalcones
publisher Elsevier B.V.
publishDate 2017
url http://eprints.utm.my/id/eprint/75480/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018957104&doi=10.1016%2fj.cdc.2017.04.004&partnerID=40&md5=04d8ce2afc200329b1527e2012ce8673
_version_ 1643657075317800960

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