A clustering-based preprocessing method for the elimination of unwanted residuals in metabolomic data

• Main Authors: Wang, W., Cheng, K. K., Deng, L., Xu, J., Shen, G., Griffin, J. L., Dong, J.
• Format: Article
• Published: Springer New York LLC 2017
• Subjects: TP Chemical technology
• Online Access: http://eprints.utm.my/id/eprint/76957/; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85006757598&doi=10.1007%2fs11306-016-1146-y&partnerID=40&md5=7c26f1e3daaa1340ae08c70be1798666
• Institution: Universiti Teknologi Malaysia

Introduction: The metabolome of a biological system is affected by multiple factors including factor of interest (e.g. metabolic perturbation due to disease) and unwanted factors or factors which are not primarily the focus of the study (e.g. batch effect, gender, and level of physical activity). Re...