Optimisation of alpha mangostin extraction using supercritical CO2 from garcinia mangostana

• Main Authors: Abdul Hamid, Mariani, Abu Bakar, Norshamiza, Chang, Seo Park, Ramli, Faiqah, Wan Sulaiman, Wan Rosli
• Format: Article
• Published: AIDIC Servizi S.r.l. 2018
• Subjects: TP Chemical technology
• Online Access: http://eprints.utm.my/id/eprint/84387/; https://doi.org/10.3303/CET1863097
• Institution: Universiti Teknologi Malaysia

This study is designed to optimise the extraction of α mangostin using supercritical carbon dioxide. The extraction parameters were optimised by Box Behnken Design (BBD) with 17-run experiments. The maximum yield of α mangostin is 58.7 wt% under optimum conditions as follows: extraction pressure of 20.01 MPa, the temperature of 46.25 ° C and percentage of co-solvent at 2.9 % of ethanol. To date, this is the first report depicting the optimisation of α mangostin from the pericarp of Garcinia Mangostana Linn using supercritical carbon dioxide.