Preparation and evaluation of the ZnO NP-Ampicillin/Sulbactam nanoantibiotic: Optimization of formulation variables using RSM coupled GA method and antibacterial activities

Nanoparticles (NPs) possessing antibacterial activity represent an effective way of overcoming bacterial resistance. In the present work, we report a novel formulation of a nanoantibiotic formed using Ampicillin/sulbactam (Ams) and a zinc oxide nanoparticle (ZnO NP). ‘ZnO NP–Ams’ nanoantibiotic form...

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Main Authors: Sharma, Nidhi, Singh, Vineeta, Pandey, Asheesh Kumar, Mishra, Bhartendu Nath, Kulsoom, Maria, Dasgupta, Nandita, Khan, Saif, El-Enshasy, Hesham A., Haque, Shafiul
Format: Article
Language:English
Published: MDPI AG 2019
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Online Access:http://eprints.utm.my/id/eprint/88620/1/HeshamAliMetwally2019_PreparationandEvaluationoftheZnONP-AmpicillinSulbactamNanoantibiotic.pdf
http://eprints.utm.my/id/eprint/88620/
http://dx.doi.org/10.3390/biom9120764
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Institution: Universiti Teknologi Malaysia
Language: English