Molecular docking and density functional theory calculations of vinpocetine and teicoplanin aglycone chiral selector

• Main Authors: Roslan, Nor Faradilla, Mustafa, Siti Fatimah Zaharah, Maarof, Hasmerya, Md. Ajeman, Siti Nadiah, Wan Ibrahim, Wan Aini
• Format: Article
• Published: Springer Science and Business Media B.V. 2020
• Subjects: QD Chemistry
• Online Access: http://eprints.utm.my/id/eprint/91334/; http://dx.doi.org/10.1007/s10847-020-01015-9
• Institution: Universiti Teknologi Malaysia

Chiral separation has been an essential issue as stereochemistry significantly influences the biological activity. In some cases, one stereoisomer may show effectiveness in pharmacology activities while the other may appear toxic. Thus, devising technology with knowledge at the fundamental level bec...