Molecular docking studies of phytochemicals from piper species as potential dual inhibitor of group X secreted phospholipase A2 (SPLA2-X) and Cyclooxygenase-2 (COX-2)

Molecular docking studies of phytochemicals from piper species as potential dual inhibitor of group X secreted phospholipase A2 (SPLA2-X) and Cyclooxygenase-2 (COX-2)

The group X secreted phospholipase A2 (sPLA2-X) and cyclooxygenase-2 (COX-2) are enzymes involved in biosynthesis of prostaglandins, a potent mediator of inflammation. The sPLA2-X hydrolysed membrane phospholipids to arachidonic acid and further converted into prostaglandins by COX-2. Previous studi...

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Bibliographic Details
Main Authors: Nadri, Muhammad Helmi, Wan Salleh, Wan Mohd. Nuzul Hakimi
Format: Article
Published: Diva Enterprises Pvt. Ltd. 2020
Subjects:
Q Science (General)
S Agriculture (General)
T Technology (General)
Online Access:http://eprints.utm.my/id/eprint/92422/
http://dx.doi.org/10.5958/0974-360X.2020.00392.3
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Institution: Universiti Teknologi Malaysia

Internet

http://eprints.utm.my/id/eprint/92422/
http://dx.doi.org/10.5958/0974-360X.2020.00392.3

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