Estimation of missing values using optimised hybrid fuzzy c-means and majority vote for microarray data
Missing values are a huge constraint in microarray technologies towards improving and identifying disease-causing genes. Estimating missing values is an undeniable scenario faced by field experts. The imputation method is an effective way to impute the proper values to proceed with the next process...
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my.utm.927092021-10-28T10:26:12Z http://eprints.utm.my/id/eprint/92709/ Estimation of missing values using optimised hybrid fuzzy c-means and majority vote for microarray data Raja Kumaran, Shamini Othman, Mohd. Shahizan Mi Yusuf, Lizawati QA75 Electronic computers. Computer science Missing values are a huge constraint in microarray technologies towards improving and identifying disease-causing genes. Estimating missing values is an undeniable scenario faced by field experts. The imputation method is an effective way to impute the proper values to proceed with the next process in microarray technology. Missing value imputation methods may increase the classification accuracy. Although these methods might predict the values, classification accuracy rates prove the ability of the methods to identify the missing values in gene expression data. In this study, a novel method, Optimised Hybrid of Fuzzy C-Means and Majority Vote (opt-FCMMV), was proposed to identify the missing values in the data. Using the Majority Vote (MV) and optimisation through Particle Swarm Optimisation (PSO), this study predicted missing values in the data to form more informative and solid data. In order to verify the effectiveness of opt-FCMMV, several experiments were carried out on two publicly available microarray datasets (i.e. Ovary and Lung Cancer) under three missing value mechanisms with five different percentage values in the biomedical domain using Support Vector Machine (SVM) classifier. The experimental results showed that the proposed method functioned efficiently by showcasing the highest accuracy rate as compared to the one without imputations, with imputation by Fuzzy C-Means (FCM), and imputation by Fuzzy C-Means with Majority Vote (FCMMV). For example, the accuracy rates for Ovary Cancer data with 5% missing values were 64.0% for no imputation, 81.8% (FCM), 90.0% (FCMMV), and 93.7% (opt-FCMMV). Such an outcome indicates that the opt-FCMMV may also be applied in different domains in order to prepare the dataset for various data mining tasks. Universiti Utara Malaysia Press 2020-10-01 Article PeerReviewed Raja Kumaran, Shamini and Othman, Mohd. Shahizan and Mi Yusuf, Lizawati (2020) Estimation of missing values using optimised hybrid fuzzy c-means and majority vote for microarray data. Journal of Information and Communication Technology, 19 (4). pp. 459-482. ISSN 1675-414X http://e-journal.uum.edu.my/index.php/jict/article/view/jict2020.19.4.1 |
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QA75 Electronic computers. Computer science Raja Kumaran, Shamini Othman, Mohd. Shahizan Mi Yusuf, Lizawati Estimation of missing values using optimised hybrid fuzzy c-means and majority vote for microarray data |
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Missing values are a huge constraint in microarray technologies towards improving and identifying disease-causing genes. Estimating missing values is an undeniable scenario faced by field experts. The imputation method is an effective way to impute the proper values to proceed with the next process in microarray technology. Missing value imputation methods may increase the classification accuracy. Although these methods might predict the values, classification accuracy rates prove the ability of the methods to identify the missing values in gene expression data. In this study, a novel method, Optimised Hybrid of Fuzzy C-Means and Majority Vote (opt-FCMMV), was proposed to identify the missing values in the data. Using the Majority Vote (MV) and optimisation through Particle Swarm Optimisation (PSO), this study predicted missing values in the data to form more informative and solid data. In order to verify the effectiveness of opt-FCMMV, several experiments were carried out on two publicly available microarray datasets (i.e. Ovary and Lung Cancer) under three missing value mechanisms with five different percentage values in the biomedical domain using Support Vector Machine (SVM) classifier. The experimental results showed that the proposed method functioned efficiently by showcasing the highest accuracy rate as compared to the one without imputations, with imputation by Fuzzy C-Means (FCM), and imputation by Fuzzy C-Means with Majority Vote (FCMMV). For example, the accuracy rates for Ovary Cancer data with 5% missing values were 64.0% for no imputation, 81.8% (FCM), 90.0% (FCMMV), and 93.7% (opt-FCMMV). Such an outcome indicates that the opt-FCMMV may also be applied in different domains in order to prepare the dataset for various data mining tasks. |
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Article |
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Raja Kumaran, Shamini Othman, Mohd. Shahizan Mi Yusuf, Lizawati |
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Raja Kumaran, Shamini Othman, Mohd. Shahizan Mi Yusuf, Lizawati |
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Raja Kumaran, Shamini |
title |
Estimation of missing values using optimised hybrid fuzzy c-means and majority vote for microarray data |
title_short |
Estimation of missing values using optimised hybrid fuzzy c-means and majority vote for microarray data |
title_full |
Estimation of missing values using optimised hybrid fuzzy c-means and majority vote for microarray data |
title_fullStr |
Estimation of missing values using optimised hybrid fuzzy c-means and majority vote for microarray data |
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Estimation of missing values using optimised hybrid fuzzy c-means and majority vote for microarray data |
title_sort |
estimation of missing values using optimised hybrid fuzzy c-means and majority vote for microarray data |
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Universiti Utara Malaysia Press |
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2020 |
url |
http://eprints.utm.my/id/eprint/92709/ http://e-journal.uum.edu.my/index.php/jict/article/view/jict2020.19.4.1 |
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