Voltammetric immunoassay for the human blood clotting factor IX by using nanogapped dielectrode junctions modified with gold nanoparticle-conjugated antibody

• Main Authors: Gopinath, S.C.B., Perumal, V., Rao, B.S., Md Arshad, M.K., Voon, C.H., Lakshmipriya, T., Haarindraprasad, R., Vijayakumar, T., Chen, Y., Hashim, U.
• Format: Article
• Published: Springer-Verlag Wien 2017
• Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85022088582&doi=10.1007%2fs00604-017-2389-7&partnerID=40&md5=7734e3bf126ecdb117086fd99b866157; http://eprints.utp.edu.my/19348/
• Institution: Universiti Teknologi Petronas

The authors describe an electrochemical method for the determination of the blood clotting factor IX (FIX). A nanogapped dielectrode (with a < 100 nm junction) was modified with antibody against FIX, and the resulting system was characterized by both impedance spectroscopy and voltammetry. In ord...