Visualizing hyperactivation in neurodegeneration based on prefrontal oxygenation: A comparative study of mild Alzheimer's disease, mild cognitive impairment, and healthy controls

• Main Authors: Yap, K.H., Ung, W.C., Ebenezer, E.G.M., Nordin, N., Chin, P.S., Sugathan, S., Chan, S.C., Yip, H.L., Kiguchi, M., Tang, T.B.
• Format: Article
• Published: Frontiers Media S.A. 2017
• Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85030153101&doi=10.3389%2ffnagi.2017.00287&partnerID=40&md5=01b7257646a7a8c1c9783ebb5f8d9f5d; http://eprints.utp.edu.my/19393/
• Institution: Universiti Teknologi Petronas

Background: Cognitive performance is relatively well preserved during early cognitive impairment owing to compensatory mechanisms. Methods: We explored functional near-infrared spectroscopy (fNIRS) alongside a semantic verbal fluency task (SVFT) to investigate any compensation exhibited by the prefr...