Flow Visualization and Characterization of an Artery Model with Stenosis

Cardiovascular diseases, principally atherosclerosis, are responsible for 30% of world deaths. Atherosclerosis is due to the formation of plaque. The fatty plaque may be at risk of rupture, leading typically to stroke and heart attack. The plaque is usually associated with a high degree of lumen red...

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Main Author: Shuib, Anis
Format: Citation Index Journal
Published: WASET Journal 2011
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Online Access:http://eprints.utp.edu.my/7475/1/v62-19.pdf
http://eprints.utp.edu.my/7475/2/v62-19.pdf
http://eprints.utp.edu.my/7475/
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Institution: Universiti Teknologi Petronas
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spelling my.utp.eprints.74752017-01-19T08:22:08Z Flow Visualization and Characterization of an Artery Model with Stenosis Shuib, Anis T Technology (General) RZ Other systems of medicine TA Engineering (General). Civil engineering (General) Cardiovascular diseases, principally atherosclerosis, are responsible for 30% of world deaths. Atherosclerosis is due to the formation of plaque. The fatty plaque may be at risk of rupture, leading typically to stroke and heart attack. The plaque is usually associated with a high degree of lumen reduction, called a stenosis.It is increasingly recognized that the initiation and progression of disease and the occurrence of clinical events is a complex interplay between the local biomechanical environment and the local vascular biology. The aim of this study is to investigate the flow behavior through a stenosed artery. A physical experiment was performed using an artery model and blood analogue fluid. An axisymmetric model constructed consists of contraction and expansion region that follow a mathematical form of cosine function. A 30% diameter reduction was used in this study. The flow field was measured using particle image velocimetry (PIV). Spherical particles with 20μm diameter were seeded in a water-glycerol-NaCl mixture. Steady flow Reynolds numbers are 250. The area of interest is the region after the stenosis where the flow separation occurs. The velocity field was measured and the velocity gradient was investigated. There was high particle concentration in the recirculation zone. High velocity gradient formed immediately after the stenosis throat created a lift force that enhanced particle migration to the flow separation area. WASET Journal 2011-12-25 Citation Index Journal PeerReviewed text/html http://eprints.utp.edu.my/7475/1/v62-19.pdf application/pdf http://eprints.utp.edu.my/7475/2/v62-19.pdf Shuib, Anis (2011) Flow Visualization and Characterization of an Artery Model with Stenosis. [Citation Index Journal] http://eprints.utp.edu.my/7475/
institution Universiti Teknologi Petronas
building UTP Resource Centre
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Petronas
content_source UTP Institutional Repository
url_provider http://eprints.utp.edu.my/
topic T Technology (General)
RZ Other systems of medicine
TA Engineering (General). Civil engineering (General)
spellingShingle T Technology (General)
RZ Other systems of medicine
TA Engineering (General). Civil engineering (General)
Shuib, Anis
Flow Visualization and Characterization of an Artery Model with Stenosis
description Cardiovascular diseases, principally atherosclerosis, are responsible for 30% of world deaths. Atherosclerosis is due to the formation of plaque. The fatty plaque may be at risk of rupture, leading typically to stroke and heart attack. The plaque is usually associated with a high degree of lumen reduction, called a stenosis.It is increasingly recognized that the initiation and progression of disease and the occurrence of clinical events is a complex interplay between the local biomechanical environment and the local vascular biology. The aim of this study is to investigate the flow behavior through a stenosed artery. A physical experiment was performed using an artery model and blood analogue fluid. An axisymmetric model constructed consists of contraction and expansion region that follow a mathematical form of cosine function. A 30% diameter reduction was used in this study. The flow field was measured using particle image velocimetry (PIV). Spherical particles with 20μm diameter were seeded in a water-glycerol-NaCl mixture. Steady flow Reynolds numbers are 250. The area of interest is the region after the stenosis where the flow separation occurs. The velocity field was measured and the velocity gradient was investigated. There was high particle concentration in the recirculation zone. High velocity gradient formed immediately after the stenosis throat created a lift force that enhanced particle migration to the flow separation area.
format Citation Index Journal
author Shuib, Anis
author_facet Shuib, Anis
author_sort Shuib, Anis
title Flow Visualization and Characterization of an Artery Model with Stenosis
title_short Flow Visualization and Characterization of an Artery Model with Stenosis
title_full Flow Visualization and Characterization of an Artery Model with Stenosis
title_fullStr Flow Visualization and Characterization of an Artery Model with Stenosis
title_full_unstemmed Flow Visualization and Characterization of an Artery Model with Stenosis
title_sort flow visualization and characterization of an artery model with stenosis
publisher WASET Journal
publishDate 2011
url http://eprints.utp.edu.my/7475/1/v62-19.pdf
http://eprints.utp.edu.my/7475/2/v62-19.pdf
http://eprints.utp.edu.my/7475/
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