Synaptic Plasticity and the Mechanism of Alzheimer's Disease

A biochemical hypothesis - that Alzheimer's disease (AD) is a progressive cerebral amyloidosis caused by the aggregation of the amyloid b-protein (Ab) - preceded and enabled the discovery of etiologies. This volume serves as a record focused on bringing together investigators at the forefront o...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
مؤلفون آخرون: Selkoe, Dennis J.
التنسيق: كتاب
اللغة:English
منشور في: Springer 2017
الموضوعات:
616
الوصول للمادة أونلاين:http://repository.vnu.edu.vn/handle/VNU_123/26143
الوسوم: إضافة وسم
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المؤسسة: Vietnam National University, Hanoi
اللغة: English
الوصف
الملخص:A biochemical hypothesis - that Alzheimer's disease (AD) is a progressive cerebral amyloidosis caused by the aggregation of the amyloid b-protein (Ab) - preceded and enabled the discovery of etiologies. This volume serves as a record focused on bringing together investigators at the forefront of elucidating the structure and function of hippocampal synapses with investigators focused on understanding how early assemblies of Ab may compromise some of these synapses.