Sparking Signals

Sparking Signals

Protein phosphorylation is an essential post-translational modification that modulates cell–cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance...

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Other Authors: Baier, G.
Format: Book
Language:English
Published: Springer 2017
Subjects:
Biomedical
Life Sciences
Online Access:http://repository.vnu.edu.vn/handle/VNU_123/30172
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Institution: Vietnam National University, Hanoi
Language: English
id oai:112.137.131.14:VNU_123-30172
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spelling oai:112.137.131.14:VNU_123-301722020-05-13T01:41:40Z Sparking Signals Baier, G. Schraven, B. Zügel, U. von Bonin, A.. Biomedical Life Sciences Protein phosphorylation is an essential post-translational modification that modulates cell–cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups. 2017-04-18T00:35:59Z 2017-04-18T00:35:59Z 2008 Book 978-3-540-73500-7 http://repository.vnu.edu.vn/handle/VNU_123/30172 en 193 p. application/pdf Springer
institution Vietnam National University, Hanoi
building VNU Library & Information Center
country Vietnam
collection VNU Digital Repository
language English
topic Biomedical
Life Sciences
spellingShingle Biomedical
Life Sciences
Sparking Signals
description Protein phosphorylation is an essential post-translational modification that modulates cell–cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups.
author2 Baier, G.
author_facet Baier, G.
format Book
title Sparking Signals
title_short Sparking Signals
title_full Sparking Signals
title_fullStr Sparking Signals
title_full_unstemmed Sparking Signals
title_sort sparking signals
publisher Springer
publishDate 2017
url http://repository.vnu.edu.vn/handle/VNU_123/30172
_version_ 1680968554554327040

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