Different types of smart nanogel for targeted delivery

• Main Authors: Qureshi, Mohammad Amir, Khatoon, Fehmeeda
• Format: Article
• Language: English
• Published: Elsevier 2019
• Subjects: PH sensitive; Temperature sensitive; Magnetic field sensitive; Light sensitive; Degradable; Nanogels
• Online Access: http://repository.vnu.edu.vn/handle/VNU_123/67728; https://doi.org/10.1016/j.jsamd.2019.04.004
• Institution: Vietnam National University, Hanoi

Decades of massive works have developed different carriers, lipoproteins, liposomes, ionic liquids, surfactants and nanogels, to enhance the targeted transportation of drugs, to reduce the side effects and to achieve controllable action on the curative sites. The word ‘nanogels’ is defined as the hydrogel nanoparticles with tunable size of 1e1000 nm formed by physical or chemical cross linked networks. The conventional challenges of solubility, substandard pharmacokinetics, in-vivo stability and toxicity, are being overcome by nanogels and other carriers. The reviewed nanogels in this article are purely based on pH, temperature, magnetic field, light and on combination of them. The discussed information will be very helpful to design a targeted delivery vehicle by specifically using photo-sensitive core-shell multisensitive nanogels