Iron oxide (Fe2O3) nanoparticles modified carbon paste electrode as an advanced material for electrochemical investigation of paracetamol and dopamine

• Main Authors: Vinay, M M, Nayaka, Y. Arthoba
• Format: Article
• Language: English
• Published: Elsevier 2019
• Subjects: Carbon paste electrode; Differential pulse voltammetry; Electrochemical impedance spectroscopy; Iron oxide nanoparticles
• Online Access: http://repository.vnu.edu.vn/handle/VNU_123/67888; https://doi.org/10.1016/j.jsamd.2019.07.006
• Institution: Vietnam National University, Hanoi

Electrochemical behaviors of paracetamol (PA) and dopamine (DA) have been investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV) and square wave voltammetry (SWV) using a selective and sensitive iron oxide (Fe2O3) nanoparticle modified carbon paste electrode (IOCPE). The PA and DA showed anodic peak potential at 0.458 V and 0.247 V and cathodic peak potential at 0.088 V and 0.11 V (vs Ag/AgCl), respectively. In DPV mode PA and DA gave linear response over the concentration range of 2 to 150 μM (R2 = 0.998) and 2 to 170 μM (R2 = 0.989), respectively. The limit of detection (LOD = 3s/m) for PA and DA were found to be 1.16 and 0.79 μM, respectively. IOCPE possess excellent electrocatalytic activity towards the determination of PA and DA. The proposed method could be successfully validated for the simultaneous and individual determination of PA and DA present in pharmaceutical and real samples