From protein structure to function with bioinformatics

This book is about protein structural bioinformatics and how it can help understand and predict protein function. It covers structure-based methods that can assign and explain protein function based on overall folds, characteristics of protein surfaces, occurrence of small 3D motifs, protein-protein...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
مؤلفون آخرون: Rigden, Daniel John
التنسيق: كتاب
اللغة:English
منشور في: Springer 2020
الموضوعات:
الوصول للمادة أونلاين:http://repository.vnu.edu.vn/handle/VNU_123/90747
الوسوم: إضافة وسم
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المؤسسة: Vietnam National University, Hanoi
اللغة: English
الوصف
الملخص:This book is about protein structural bioinformatics and how it can help understand and predict protein function. It covers structure-based methods that can assign and explain protein function based on overall folds, characteristics of protein surfaces, occurrence of small 3D motifs, protein-protein interactions and on dynamic properties. Such methods help extract maximum value from new experimental structures, but can often be applied to protein models. The book also, therefore, provides comprehensive coverage of methods for predicting or inferring protein structure, covering all structural classes from globular proteins and their membrane-resident counterparts to amyloid structures and intrinsically disordered proteins. The book is split into two broad sections, the first covering methods to generate or infer protein structure, the second dealing with structure-based function annotation. Each chapter is written by world experts in the field.