Lipidomics of stem cells

• Other Authors: Pébay, Alice ; Wong, Raymond C. B.
• Format: Book
• Language: English
• Published: Springer 2020
• Subjects: Lipids ; Stem cells ; Tế bào gốc; 572.57 LIP 2017
• Online Access: http://repository.vnu.edu.vn/handle/VNU_123/90751
• Institution: Vietnam National University, Hanoi

This book combines the current knowledge on the role of lipids in stem cell pluripotency and differentiation. It showcases various approaches to the study of lipids and focuses on various types of stem cells and specific lipids driving maintenance or differentiation. The volume includes chapters reviewing roles of specific lipids in pluripotency, neurogenesis and exocytosis as well as in cancer stem cells. Examples of different classes of lipidsℓ́ℓsuch as sphingolipids, lysophospholipids, cannabinoids and neutral lipidsℓ́ℓare described and illustrate the vast biological effects of this class of molecules. The international contributors are all recognized experts in their respective fields. Covering the various aspects of the topic, Lipidomics of Stem Cells provides an up-to-date snapshotℓ́ℓunique among the literatureℓ́ℓof where the lipid world is in terms of understanding the roles of lipids in stem cell biology. It provides an essential reference for stem cell biologists, lipid biologists, development biologists, students, academics and clinicians in related areas.Preface; Contents; Contributors; Chapter 1: Lysophosphatidic Acid and€Sphingosine- 1-ƯPhosphate in€Pluripotent Stem Cells; 1.1 Introduction; 1.2 Lipid Homeostasis in€Stem Cell Biology; 1.3 LPA and€S1P Synthesis and€Degradation; 1.3.1 LPA; 1.3.2 S1P; 1.4 LPA and€S1P Signaling; 1.5 Role of€LPA and€S1P in€Pluripotent Stem Cells; 1.6 Discussion and€Conclusion; References; Chapter 2: Morphogenetic Sphingolipids in€Stem Cell Differentiation and€Embryo Development; 2.1 Ceramide and€Its Derivatives; 2.1.1 Ceramide and€Ceramide-Enriched Compartments; 2.1.1.1 Ceramide and€Cilia.