Wound Healing Activity of Herbal Ointment Containing the Ethanolic Leaf Extract of Gumamela (Hibiscus rosa-sinensis)

• Main Authors: Gutierrez, Marjorie Lama, Algones, Sharmine Mae Cabanggangan, Andres, Isabella May Viado, Tabun-tabon, Jason Romeral
• Format: text
• Published: Animo Repository 2021
• Subjects: hibiscus rosa-sinensis; gumamela ointment; wound healing activity; wound splint model; ethanolic leaf extract
• Online Access: https://animorepository.dlsu.edu.ph/conf_shsrescon/2021/paper_fnh/10; https://animorepository.dlsu.edu.ph/context/conf_shsrescon/article/1623/viewcontent/FNH_Wound_Healing_Activity_of_Herbal_Ointment_Containing_the_Ethanolic.pdf
• Institution: De La Salle University

The wound healing process is a multi-step cellular and biochemical process. For wound healing, antibiotics; preservatives; desalination agents; chemicals; and others are used. Some of these synthetic drugs are limited due to side effects. For this reason, the use of medicinal plants for wound healing has increased in popularity over the years due to the reduction of side effects. In fact, previous studies proved that Hibiscus rosa-sinensis (gumamela) extract can be used to treat wounds. Thus, the purpose of this study intends to evaluate the wound healing potentials of the formulated herbal ointment containing the gumamela ethanolic leaf extracts. The gumamela leaf ethanolic extract was mixed into the ointment foundation. The herbal ointment was then formulated. For the wound healing study, untreated and gumamela ointment treated wounds of albino mouse were observed to have a comparison after the experimentation. The physicochemical parameters of gumamela ointment including color, odor, washability, solubility, consistency, and pH level were all evaluated, and the results were satisfactory. Throughout the experimental period, there was a larger wound closure percentage in the wound treated with gumamela ointment as compared to the untreated. Hence, this finding clearly indicates that the ointment containing the gumamela leaf extract can enhance the healing of a wound as indicated by improved rates of wound closure.